BIOMOLECULES AND ENZYMES

Detailed explanation-1: -In this article I describe the relevance of a temperature near 37 degrees C to the activities of all enzymes in man, intracellular and extracellular. I conclude that 37 degrees C is to be favored as the temperature for assaying all parameters in human biochemistry affected by temperature.

Detailed explanation-2: -Enzymes are highly temperature sensitive, and are not functional at low temperatures and undergo denaturation at very high temperatures. Most of the enzymes in human body function optimally at the physiological temperature that is 37∘C.

Detailed explanation-3: -This optimal temperature is usually around human body temperature (37.5 oC) for the enzymes in human cells. Above this temperature the enzyme structure begins to break down (denature) since at higher temperatures intra-and intermolecular bonds are broken as the enzyme molecules gain even more kinetic energy.

Detailed explanation-4: -Scientists have found the reason why our body temperature is 37°C. Apparently it’s the perfect balance, as it’s warm enough to prevent fungal infection but not so hot that we need to eat nonstop to maintain our metabolism. Scientists have always wondered why advanced mammals are so hot compared to other animals.

Detailed explanation-5: -Optimum temperature is the temperature at which enzyme activity is maximum. In humans, this temperature is 37.5oC that is same as the normal body temperature.