BIOMOLECULES AND ENZYMES

Detailed explanation-1: -The altering of a protein’s molecular structure is known as denaturation. During denaturation, many of the weak connections and interactions (such as hydrogen bonds) inside a protein molecule that is responsible for the highly ordered structure of the protein in its natural (native) state, are broken.

Detailed explanation-2: -Many enzymes change shape when substrates bind. This is termed “induced fit", meaning that the precise orientation of the enzyme required for catalytic activity can be induced by the binding of the substrate.

Detailed explanation-3: -Denaturation of enzymes causes bonds to be broken, structure to be disrupted and it stops functioning. This happens to enzymes when they are exposed to extreme, unsuitable conditions, for instance, high temperatures or extreme pH levels.

Detailed explanation-4: -However, extreme high temperatures can cause an enzyme to lose its shape (denature) and stop working. pH: Each enzyme has an optimum pH range. Changing the pH outside of this range will slow enzyme activity. Extreme pH values can cause enzymes to denature.