BIOMOLECULES AND ENZYMES

BIOLOGY

ENZYMES

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Why is the induced fit model a better representation of enzyme action compared to the lock and key model?
A
Shows that the enzymes active site moulds around the substrate
B
Shows that the enzymes active site is the exact same shape as the substrate
C
Bonds are distorted when active site moulds around substrate
D
Enzyme collides with such a force with the substrate that the bonds are weakened
Explanation: 

Detailed explanation-1: -Unlike the lock-and-key model, the induced fit model shows that enzymes are rather flexible structures in which the active site continually reshapes by its interactions with the substrate until the time the substrate is completely bound to it.

Detailed explanation-2: -The main difference between induced fit and lock and key model is that in the induced fit model, the active site of the enzyme does not completely fit to the substrate whereas in the lock and key model, the active site of the enzyme is the complement of the substrate and hence, it precisely fits to the substrate.

Detailed explanation-3: -Explanation: The lock and key model states that the active site of an enzyme precisely fits a specific substrate. The induced fit model states that the active site of an enzyme will undergo a conformational change when binding a substrate, to improve the fit.

Detailed explanation-4: -In addition, the induced fit model is better able to explain how catalysis actually occurs. A conformational change, which would place stress on the bonds within the substrate can explain how bonds would break in order for the products to form. This makes the induced fit model the more widely accepted model of the two.

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