BIOMOLECULES AND ENZYMES

Detailed explanation-1: -Leptin is a hormone primarily produced by the adipose tissue in proportion to the size of fat stores, with a primary function in the control of lipid reserves. Besides adipose tissue, leptin is also produced by other tissues, such as the stomach, placenta, and mammary gland.

Detailed explanation-2: -Leptin is secreted mainly by white adipose tissue. Leptin levels are correlated with the amount of fat (reflecting the amount of energy stored), and with changes in caloric intake. Other factors can regulate the circulating leptin levels.

Detailed explanation-3: -Leptin is secreted mainly by white adipose tissue, and levels are positively correlated with the amount of body fat (3). Like many other hormones, leptin is secreted in a pulsatile fashion and has a significant diurnal variation with higher levels in the evening and early morning hours (4, 5).

Detailed explanation-4: -It is now widely accepted that white adipose tissue (WAT) secretes a number of peptide hormones, including leptin, several cytokines, adipsin and acylation-stimulating protein (ASP), angiotensinogen, plasminogen activator inhibitor-1 (PAI-1), adiponectin, resistin etc., and also produces steroids hormones.

Detailed explanation-5: -Leptin production Leptin is produced and secreted predominantly from adipose tissue into the circulation. Circulating leptin levels positively reflect adipose tissue size, and communicate energy storage status to the brain [6, 7].