BIOMOLECULES AND ENZYMES

Detailed explanation-1: -Your thyroid releases calcitonin based on the level of calcium in your blood. When your blood calcium levels increase, your thyroid releases calcitonin in higher quantities. When blood calcium levels decrease, your thyroid decreases the amount of calcitonin it releases.

Detailed explanation-2: -Calcitonin reduces calcium levels in the blood by two main mechanisms: It inhibits the activity of osteoclasts, which are the cells responsible for breaking down bone. When bone is broken down, the calcium contained in the bone is released into the bloodstream.

Detailed explanation-3: -Calcitonin secretion is stimulated by increases in the serum calcium concentration and calcitonin protects against the development of hypercalcemia. Calcitonin is also stimulated by gastrointestinal hormones such as gastrin.

Detailed explanation-4: -While HPT occurs when one or more malfunctioning parathyroid glands produce an excess amount of PTH and raise the blood calcium level, calcitonin does not play a major role in HPT. Also, whereas calcitonin helps lower the body’s calcium levels, PTH helps increase the body’s calcium levels.

Detailed explanation-5: -If too much calcitonin is found in the blood, it may be a sign of a type of thyroid cancer called medullary thyroid cancer (MTC). High levels may also be a sign of other thyroid diseases that can put you at a higher risk for getting MTC.