BIOMOLECULES AND ENZYMES

Detailed explanation-1: -Replication occurs in three major steps: the opening of the double helix and separation of the DNA strands, the priming of the template strand, and the assembly of the new DNA segment. During separation, the two strands of the DNA double helix uncoil at a specific location called the origin.

Detailed explanation-2: -DNA synthesis begins in S phase as the replicative helicase unwinds and separates the two strands of the DNA double helix [7]. As the helicase unwinds DNA, DNA polymerase synthesizes DNA utilizing the exposed single stranded DNA as a template.

Detailed explanation-3: -Step 2: Primer Binding. The leading strand is the simplest to replicate. Once the DNA strands have been separated, a short piece of RNA called a primer binds to the 3’ end of the strand. The primer always binds as the starting point for replication.