BIOMOLECULES AND ENZYMES

Detailed explanation-1: -The given statement is (a)True. Denaturation of protein is always permanent as it is an irreversible process.

Detailed explanation-2: -In many cases, denaturation is reversible (the proteins can regain their native state when the denaturing influence is removed). This process can be called renaturation.

Detailed explanation-3: -The protein that makes up the enzyme is denatured when it is exposed to extremes of temperature, pH or salty condition. This denaturation can be reversed.

Detailed explanation-4: -Protein denaturation is said to be irreversible when the denatured state achieved by increasing temperature or by using chemical denaturants is unable to return to the native, biologically functional state upon removal of the factor that caused denaturation.

Detailed explanation-5: -In many situations, denaturation is reversible. Proteins can not regain their native structure until the denaturing agent is removed. However, there can be some situations when denaturation is irreversible like the exposure of proteins to extreme heat.