BIOMOLECULES AND ENZYMES

Detailed explanation-1: -The denaturation of the proteins of egg white by heat-as when boiling an egg-is an example of irreversible denaturation.

Detailed explanation-2: -Although denaturation can be irreversible, an example of reversible denaturing in proteins is the modern permanent wave technique for curling or straightening hair.

Detailed explanation-3: -In denaturation, the peptide bonds are not affected, but the H-bonds, disulfide bonds, salt bridges and hydrophobic interactions can all be disrupted, leading to the consecutive alteration of 4o, 3o and 2o structure.

Detailed explanation-4: -Within a restricted range of pH and protein concentration crystalline chymotrypsinogen undergoes thermal denaturation which is wholly reversed upon cooling.