CLINICAL MEDICINE

MEDICINE

ENDOCRINOLOGY

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Major stimulus of growth hormone secretion
A
Sleep
B
Somatostatin
C
Fasting and High protein diet
D
Levodopa
Explanation: 

Detailed explanation-1: -Altered hypothalamic activity associated with initiation of sleep results in a major peak of growth hormone secretion unrelated to hypoglycemia or changes in cortisol and insulin secretion.

Detailed explanation-2: -The release of GH is greatly enhanced during sleep, especially early in the night; this is associated with the appearance of delta waves on electroencephalography, which are characteristic of SWS [5], and increased release of GH-releasing hormone (GHRH) in the hypothalamus [6].

Detailed explanation-3: -Growth hormone levels are increased by sleep, stress, exercise and low glucose levels in the blood. They also increase around the time of puberty.

Detailed explanation-4: -Mean GH levels were higher during slow wave sleep (SWS) compared with other sleep stages. During sleep after deprivation, GH secretion was prolonged, and second GH peaks occurred in three subjects which were not associated with SWS.

Detailed explanation-5: -Melatonin, released by the pineal gland, controls your sleep patterns. Levels increase at night time, making you feel sleepy. While you’re sleeping, your pituitary gland releases growth hormone, which helps your body to grow and repair itself.

There is 1 question to complete.