MEDICINE
HAEMATOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Red blood cells burst and die
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Red blood cells are clumped together and become non-functional
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Antibodies bind to the antigens and then render the red blood cell non-functional
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A system in which transfusions can occur
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Detailed explanation-1: -Agglutination is the process that occurs if an antigen is mixed with its corresponding antibody called isoagglutinin. This term is commonly used in blood grouping. This occurs in biology in two main examples: The clumping of cells such as bacteria or red blood cells in the presence of an antibody or complement.
Detailed explanation-2: -Landsteiner explained that the reactions between the RBCs and serum were related to the presence of markers (antigens) on the RBCs and antibodies in the serum. Agglutination occurred when the RBC antigens were bound by the antibodies in the serum.
Detailed explanation-3: -The binding of RBCs by anti-A or anti-B IgM antibodies interacting with the corresponding antigens at their surface lead to agglutination.
Detailed explanation-4: -If the plasma is mixed with Type A blood, the cells will agglutinate, or clump together, from the reaction of the Type A antigens and the anti-A antibodies.
Detailed explanation-5: -Agglutination reactions where the antigens are found naturally on a particle are known as direct agglutination. In active agglutination, direct agglutination of particulate antigen with specific antibody occurs. Direct bacterial agglutination uses whole pathogens as a source of antigen.