HORTICULTURE

HORTICULTURE SCIENCE

GENERAL AGRICULTURE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Endonuclease which cleaves dsRNA is
A
ricer
B
dicer
C
RISC
D
slicer
Explanation: 

Detailed explanation-1: -Dicer is a multi-domain RNase III-related endonuclease responsible for processing double-stranded RNA (dsRNA) to small interfering RNAs (siRNAs) during a process of RNA interference (RNAi). It also catalyses excision of the regulatory microRNAs from their precursors.

Detailed explanation-2: -RNase III is an archetypal endoRNase that cleaves dsRNA.

Detailed explanation-3: -Dicer ribonucleases cleave double-stranded RNA (dsRNA) precursors to generate microRNAs (miRNAs) and small interfering RNAs (siRNAs) (1, 2). In concert with Argonautes, these small RNAs bind complementary mRNAs to downregulate their expression.

Detailed explanation-4: -The RNAi pathway is initiated by the enzyme dicer (see below), which cleaves long, double-stranded RNA (dsRNA) molecules into short fragments of 20–25 base pairs.

There is 1 question to complete.