HORTICULTURE

Detailed explanation-1: -The most commonly used drug for thrombolytic therapy is tissue plasminogen activator (tPA), but other drugs can do the same thing. Ideally, you should receive thrombolytic medicines within the first 30 minutes after arriving at the hospital for treatment. A blood clot can block the arteries to the heart.

Detailed explanation-2: -Anticoagulants. Anticoagulants, such as heparin, warfarin, dabigatran, apixaban, and rivaroxaban, are medications that thin the blood and help to dissolve blood clots.

Detailed explanation-3: -tPA quickly dissolves the clots that cause many strokes. By opening a blocked blood vessel and restoring blood flow, tPA can reduce the amount of damage to the brain that can occur during a stroke.

Detailed explanation-4: -Systemic thrombolysis uses thrombolytic drugs and medications that circulate throughout your body to dissolve clots and prevent future blockages. Penn physicians most often use systemic thrombolysis after an emergency such as a heart attack, pulmonary embolism or stroke.

Detailed explanation-5: -tPA attaches to the fibrin on the clot surface. It activates the fibrin-bound plasminogen. Plasmin is subsequently cleaved from the plasminogen affiliated with the fibrin. The plasmin breaks up the molecules of fibrin, and the clot dissolves.