HORTICULTURE SCIENCE
PLANT BIOTECHNOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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What bacteria were genetically engineered to produce insulin?
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E. coli
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Salmonella
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Yeast
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Listeria
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Explanation:
Detailed explanation-1: -Nowadays, recombinant human insulin is mainly produced either in E. coli or Saccharomyces cerevisiae.
Detailed explanation-2: -coli by recombinant DNA technology. Synthetic genes for human insulin A and B chains are cloned separately in plasmid pBR322. The cloned synthetic genes are then fused to an Escherichia coli -galactosidase gene to provide efficient transcription and translation and a stable precursor protein.
Detailed explanation-3: -In 1978, the biotechnology firm “Genentech” produced human insulin using the bacteria E. coli, making insulin the first-ever human protein manufactured through biotechnology.
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