OBJECTIVE LIFE SCIENCE
SIGNALLING IMMUNOLOGY CANCER
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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IgE antibodies act by cross-linking what kind of receptor on the surfaces of innate immune cells?
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Fc receptors
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PAMPs
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G-protein-linked receptors
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None of the above
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Explanation:
Detailed explanation-1: -Fc Receptors. There are two IgE receptors: FcRI is the high-affinity IgE receptor that is expressed by mast cells and basophils and by dendritic cells and Langerhans cells in the skin. 39.
Detailed explanation-2: -Cross-linking of the IgE-FcRI complex triggers mast cell activation and the release of substances that cause the symptoms of allergy (Figure 1A; Kinet, 1999).
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