PHYSIOLOGY
EXCITATION CONTRACTION COUPLING
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Question
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In excitation-contraction coupling:
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The muscle action potential moves along the sarcolemma and down the transverse tubules
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Ca2+ released from the sarcoplasmic reticulum binds to tropomyosin
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Troponin blocks binding of myosin heads to actin filaments
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Relaxation occurs when Ca++ is excreted from the muscle fiber
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Explanation:
Detailed explanation-1: -Within these cells, electrical excitation during the action potential is linked to cell shortening by a process known as excitation-contraction (EC) coupling. In mammalian heart, this process is made possible by membrane invaginations called t-tubules which propagate the action potential into the cell interior.
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