PHYSIOLOGY
MUSCLE ENERGETICS GLYCOLYSIS
Question
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The major energy generating step during glycolysis is
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hexokinase
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phosphofructokinase
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phosphoglycerate kinase
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glyceraldehyde-3-P dehydrogenase
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Explanation:
Detailed explanation-1: -Glyceraldehyde 3-phosphate dehydrogenase (abbreviated GAPDH) (EC 1.2. 1.12) is an enzyme of about 37kDa that catalyzes the sixth step of glycolysis and thus serves to break down glucose for energy and carbon molecules.
Detailed explanation-2: -Glyceraldehyde-3-phosphate dehydrogenase regulates activation of c-Jun N-terminal kinase under oxidative stress. Crotonylation of GAPDH regulates human embryonic stem cell endodermal lineage differentiation and metabolic switch.
Detailed explanation-3: -Glyceraldehyde-3-phosphate dehydrogenase (GPDA) is an enzyme that catalyzes the sixth step of glycolysis.
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