PHYSIOLOGY
EXCITATION CONTRACTION COUPLING
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Transverse tubule (or T-Tubule)
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myotubule
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sarcolemma
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sarcomeres
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Detailed explanation-1: -Transverse tubule T-tubules are invaginations of the plasma membrane, which are present exclusively in striated muscle. Their role is to maintain the SR calcium store under the tight control of membrane depolarization via the voltage sensor channel DHPR [2].
Detailed explanation-2: -The most recognized function of t-tubules is regulation of cardiac EC coupling by concentrating voltage-gated L-type calcium channels (LTCCs) and positioning them in close proximity to calcium sense and release channels, ryanodine receptors (RyRs), at the junctional membrane of sarcoplasmic reticulum (jSR).
Detailed explanation-3: -A Muscle Contraction Is Triggered When an Action Potential Travels Along the Nerves to the Muscles. Muscle contraction begins when the nervous system generates a signal. The signal, an impulse called an action potential, travels through a type of nerve cell called a motor neuron.