MUSCLE PHYSIOLOGY

PHYSIOLOGY

MUSCLE CONTRACTION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
A build up of charge in the sarcolemma reaches ____ to begin the propagation of an action potential down the length of the sarcolemma.
A
Capacity
B
Threshold
C
Ionization
D
Critical
Explanation: 

Detailed explanation-1: -Propagation of an action potential along the sarcolemma is the excitation portion of excitation-contraction coupling. Recall that this excitation actually triggers the release of calcium ions (Ca++) from its storage in the cell’s SR.

Detailed explanation-2: -Through the DHPR, the action potential in the sarcolemma triggers the opening of RyR, allowing Ca++ to diffuse out of the SR and into the sarcoplasm. It is the arrival of Ca++ in the sarcoplasm that allows for the binding of actin and myosin and thus initiates contraction and shortening of sarcomeres.

Detailed explanation-3: -Excitation–Contraction Coupling. Excitation–contraction coupling is the link (transduction) between the action potential generated in the sarcolemma and the start of a muscle contraction.

There is 1 question to complete.