MUSCLE PHYSIOLOGY

PHYSIOLOGY

MUSCLE CONTRACTION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Actin filaments are bound to the edges of the sarcomere, also known as the ____
A
M-Line
B
H-Zone
C
Z-Disc
D
A-Band
Explanation: 

Detailed explanation-1: -Thin filaments attach to a protein in the Z disc called alpha-actinin and occur across the entire length of the I band and partway into the A band. The region at which thick and thin filaments overlap has a dense appearance, as there is little space between the filaments.

Detailed explanation-2: -Not surprisingly, filamin, a well-studied actin-binding protein localizes at the Z-disc where it binds actin through a conserved N-terminal ABD, composed of two CH domains.

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