MUSCLE PHYSIOLOGY

PHYSIOLOGY

MUSCLE CONTRACTION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
All skeletal muscle fibers are
A
multinucleated
B
single nucleus
C
composted of no nuclei
D
none
Explanation: 

Detailed explanation-1: -Skeletal muscle cells are long, cylindrical, and striated. They are multi-nucleated meaning that they have more than one nucleus. This is because they are formed from the fusion of embryonic myoblasts. Each nucleus regulates the metabolic requirements of the sarcoplasm around it.

Detailed explanation-2: -Skeletal muscle fibers are the only muscle cells that are multinucleated with the nuclei usually referred to as myonuclei. This occurs during myogenesis with the fusion of myoblasts each contributing a nucleus to the newly formed muscle cell or myotube.

Detailed explanation-3: -Multinucleation is one mechanism adopted by cells to generate and sustain large cell sizes. Muscle cells are one of the largest cell types, which are formed by fusion of mononucleated myoblasts and contain up to several tens (invertebrates) to several hundred (vertebrates) nuclei.

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