MUSCLE PHYSIOLOGY

PHYSIOLOGY

MUSCLE CONTRACTION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Cross bridges are formed when
A
ADP and Pi released from myosin head
B
ATP binds to myosin head
C
Myosin head hydrolyse ATP
D
Tropomyosin binds to myosin binding site
E
A human dies
Explanation: 

Detailed explanation-1: -The Cross-Bridge Muscle Contraction Cycle The ATP is hydrolyzed into ADP and inorganic phosphate (Pi) by the enzyme ATPase. The energy released during ATP hydrolysis changes the angle of the myosin head into a “cocked” position, ready to bind to actin if the sites are available.

Detailed explanation-2: -Each attachment-detachment cycle between a myosin head and actin is coupled with hydrolysis of one ATP molecule.

Detailed explanation-3: -At the end of the working stroke the myosin is detached from actin by the binding of ATP. The ATP is then hydrolyzed when the myosin is either weakly attached to actin or is detached (Lymn and Taylor, 1971).

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