MUSCLE PHYSIOLOGY

PHYSIOLOGY

MUSCLE CONTRACTION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
How does myosin release actin and continue pulling more actin towards the center of the sarcomere.
A
Calcium binds to myosin and releases it from actin, allowing myosin to keep pulling actin.
B
ATP attaches to myosin and is hydrolyzed into ADP+phosphate+energy. This energy released breaks the bridge between actin and myosin.
C
ADP+phosphate+energy is hydrolyzed into ATP. This energy released breaks the bridge between actin and myosin.
D
None of the above
Explanation: 

Detailed explanation-1: -Sliding-filament model of muscle contraction. The actin filaments slide past the myosin filaments toward the middle of the sarcomere. The result is shortening of the sarcomere without any change in filament length.

Detailed explanation-2: -Myosin bound by ADP and inorganic phosphate (Pi) can then form cross-bridges with actin, and the release of ADP and Pi produces the power stroke that drives contraction. This force causes the thin actin filament to slide past the thick myosin filament and shortens the muscle.

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