PHYSIOLOGY
MUSCLE CONTRACTION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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In relation of the muscle Ca2+ concentrations increase in order to stop contraction of the muscle
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True
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False
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Either A or B
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None of the above
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Explanation:
Detailed explanation-1: -When Ca2+ was induced to increase rapidly, the relation between [Ca2+] and force exhibited hysteresis. During the onset of contraction, force at a given [Ca2+] was lower than during the muscle’s return to rest, thus suggesting the existence of a slow step(s) linking Ca2+ and force development in smooth muscle.
Detailed explanation-2: -A muscle also can stop contracting when it runs out of ATP and becomes fatigued ([link]). Ca++ ions are pumped back into the SR, which causes the tropomyosin to reshield the binding sites on the actin strands. A muscle may also stop contracting when it runs out of ATP and becomes fatigued.
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