PHYSIOLOGY
MUSCLE CONTRACTION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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True
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False
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Either A or B
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None of the above
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Detailed explanation-1: -Myosin makes up the thick filament and is a polymerised protein. It is made up of meromyosin, a monomeric protein. Meromyosin has 2 parts: a globular head with short arm, called heavy meromyosin, and the tail, called light meromyosin.
Detailed explanation-2: -HMM consists of two subunits, Heavy Meromyosin Subunit 1 and 2 (HMMS-1 and HMMS-2). The majority of myosin activity is concentrated in HMMS-1. HMMS-1 has an actin binding site and ATP binding site (myosin ATPase) that determines the rate of muscle contraction when muscle is stretched.
Detailed explanation-3: -So, the correct answer is ‘Meromyosin’.
Detailed explanation-4: -Under our experimental conditions, both expressed full-length and native myosin VI are monomeric.