MUSCLE PHYSIOLOGY

Detailed explanation-1: -EXPLANATION: The junction between a motor neuron and the sarcolemma of the muscle fibre is called the motor end plate. It is formed at the sites, where the terminal branches of the axon of a motor neuron contact with a muscle cell.

Detailed explanation-2: -The neuromuscular junction (NMJ) is a synaptic connection between the terminal end of a motor nerve and a muscle (skeletal/ smooth/ cardiac). It is the site for the transmission of action potential from nerve to the muscle.

Detailed explanation-3: -The axon terminal rests within a primary depression of sarcolemma, the primary cleft, and contains numerous small vesicles that contain acetylcholine (ACh), the neurotransmitter for excitation of skeletal myofibers. Each vesicle contains a quantum of neurotransmitter, consisting of 6000 to 8000 molecules of ACh.

Detailed explanation-4: -Synaptic cleft-the space between the axon terminal (synaptic end bulb) and the sarcolemma (motor end plate) Page 11 Neuromuscular Junction It is the the region formed by the axon terminal of the motor neuron and the motor end plate of the muscle fiber.

Detailed explanation-5: -The gap between the axon terminal of a motor neuron and the sarcolemma of a skeletal muscle cell is known as the neuromuscular junction.