MUSCLE PHYSIOLOGY

Detailed explanation-1: -The sliding filament theory is a suggested mechanism of contraction of striated muscles, actin and myosin filaments to be precise, which overlap each other resulting in the shortening of the muscle fibre length. Actin (thin) filaments combined with myosin (thick filaments) conduct cellular movements.

Detailed explanation-2: -According to the sliding filament theory, a muscle fiber contracts when myosin filaments pull actin filaments closer together and thus shorten sarcomeres within a fiber.

Detailed explanation-3: -The sliding filament theory describes the mechanism that allows muscles to contract. According to this theory, myosin (a motor protein) binds to actin. The myosin then alters its configuration, resulting in a “stroke” that pulls on the actin filament and causes it to slide across the myosin filament.

Detailed explanation-4: -This process is known as myosin-actin cycling. As the myosin S1 segment binds and releases actin, it forms what are called cross bridges, which extend from the thick myosin filaments to the thin actin filaments. The contraction of myosin’s S1 region is called the power stroke (Figure 3).

Detailed explanation-5: -According to the sliding filament theory, the myosin (thick filaments) of muscle fibers slide past the actin (thin filaments) during muscle contraction, while the two groups of filaments remain at relatively constant length.