MUSCLE PHYSIOLOGY

PHYSIOLOGY

MUSCLE CONTRACTION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The point at which the nerve cell reaches the sarcolemma of the muscle fiber is the ____
A
Neurotransmitter
B
Acetylcholine
C
Synaptic cleft
D
Neuromuscular Junction
Explanation: 

Detailed explanation-1: -Between the synaptic end bulbs of the neuron and the cell membrane of the muscle fiber (the sarcolemma) lies a space known as the synaptic cleft, which is the final component of the neuromuscular junction.

Detailed explanation-2: -The neuromuscular junction (NMJ) is a synaptic connection between the terminal end of a motor nerve and a muscle (skeletal/ smooth/ cardiac).

Detailed explanation-3: -Embedded in the sarcolemma (= fiber membrane) at the neuromuscular junction are (nicotinic) receptors for acetylcholine (ACh). This is the neurotransmitter that is released by the terminal branches of a motor neuron. An enlargement of an ACh receptor reveals that it is composed of five (5) polypeptide subunits.

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