PHYSIOLOGY
MUSCLE CONTRACTION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Activation
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Excitation-Contraction Coupling
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The Cross-Bridge Cycle
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None of the above
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Detailed explanation-1: -First coined by Alexander Sandow in 1952, the term excitation–contraction coupling (ECC) describes the rapid communication between electrical events occurring in the plasma membrane of skeletal muscle fibres and Ca2+ release from the SR, which leads to contraction.
Detailed explanation-2: -Excitation–contraction coupling describes how an electrical signal, the action potential (AP), traveling along the plasmalemma evokes calcium release from the SR in the region of the myofibrils, causing a change in actin–myosin interactions, which leads to muscle contraction.
Detailed explanation-3: -During excitation, an action potential is propagated at the muscle cell membrane. This action potential triggers the release of calcium ions within the cell, initiating contraction.