MUSCLE PHYSIOLOGY

Detailed explanation-1: -The actin filaments are attached at their plus ends to the Z disc, which includes the crosslinking protein -actinin. The myosin filaments are anchored at the M line in the middle of the sarcomere .

Detailed explanation-2: -myosin interaction with the M line. overlap of myosin and actin. actin attachments to the Z line.

Detailed explanation-3: -Actin filaments are attached to the Z-line.

Detailed explanation-4: -The sarcomeric Z-disk, the anchoring plane of thin (actin) filaments, links titin (also called connectin) and actin filaments from opposing sarcomere halves in a lattice connected by alpha-actinin.

Detailed explanation-5: -The primary function of the Z-band is the transmission of tension from one sarcomere to the next. As actin filaments are not continuous through the Z-band, the tension has to be transmitted through the Z-band assembly; hence, understanding the 3D structure is important.