MUSCLE PHYSIOLOGY

Detailed explanation-1: -The generally accepted model (the swinging-cross-bridge model) is that ATP hydrolysis drives repeated cycles of interaction between myosin heads and actin. During each cycle, conformational changes in myosin result in the movement of myosin heads along actin filaments .

Detailed explanation-2: -ATP then binds to myosin, moving the myosin to its high-energy state, releasing the myosin head from the actin active site. ATP can then attach to myosin, which allows the cross-bridge cycle to start again; further muscle contraction can occur.

Detailed explanation-3: -The ATP molecule bound to the myosin head is hydrolyzed to produce ADP and an inorganic phosphate. The hydrolysis of ATP releases the energy needed for the myosin head to be ready for another power stroke and bind to another myosin binding site further along the actin filament.