MUSCLE PHYSIOLOGY

Detailed explanation-1: -The sliding filament theory is a suggested mechanism of contraction of striated muscles, actin and myosin filaments to be precise, which overlap each other resulting in the shortening of the muscle fibre length. Actin (thin) filaments combined with myosin (thick filaments) conduct cellular movements.

Detailed explanation-2: -Sliding Filament Theory According to this theory, myosin filaments use energy from ATP to “walk” along the actin filaments with their cross bridges. This pulls the actin filaments closer together. The movement of the actin filaments also pulls the Z lines closer together, thus shortening the sarcomere.

Detailed explanation-3: -The sliding filament theory explains the process of muscle contraction during which the thin filaments slide over the thick filaments, which shortens the myofibril. Each muscle fibre has an alternate light and dark band, which contains a special contractile protein, called actin and myosin respectively.

Detailed explanation-4: -According to the sliding filament theory, the myosin (thick filaments) of muscle fibers slide past the actin (thin filaments) during muscle contraction, while the two groups of filaments remain at relatively constant length.

Detailed explanation-5: -The Sarcomere: The Basic Contractile Unit of Muscle The most popular model that describes muscular contraction is called the sliding filament theory. In this theory, active force is generated as actin filaments slide past the myosin filaments, resulting in contraction of an individual sarcomere.