MUSCLE PHYSIOLOGY

PHYSIOLOGY

MUSCLE CONTRACTION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What opens the voltage gated calcium ion channels embedded in the sarcoplasmic reticulum?
A
Binding of Acetylcholine
B
Binding of Calcium Ion
C
An Action Potential
D
Binding of Sodium Ion
Explanation: 

Detailed explanation-1: -Electrical Stimulation Depolarization of the sarcolemma leads to opening of voltage-gated Ca2+ channels and influx of Ca2+ from the extracellular space. This Ca2+ pulse can also trigger the release of intracellular Ca2+ from the sarcoplasmic reticulum (Ca2+-induced Ca2+ release, CICR).

Detailed explanation-2: -In neurons, calcium channels open in response to the binding of neurotransmitters to cell surface receptors that are permeable to calcium, such as NMDA and AMPA receptors.

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