MUSCLE PHYSIOLOGY

PHYSIOLOGY

MUSCLE CONTRACTION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
When sarcomeres shorten, what happens to individual thick and thin filaments?
A
Thin filaments shorten; thick filaments lenghten
B
Thick filaments shorten; thick filaments lengthen
C
The filaments slide past one another
D
Both filaments shorten
Explanation: 

Detailed explanation-1: -Muscle contraction occurs when sarcomeres shorten, as thick and thin filaments slide past each other, which is called the sliding filament model of muscle contraction.

Detailed explanation-2: -Muscle contraction occurs when the thin actin and thick myosin filaments slide past each other. It is generally assumed that this process is driven by cross-bridges which extend from the myosin filaments and cyclically interact with the actin filaments as ATP is hydrolysed.

Detailed explanation-3: -As a sarcomere is shortened, the zone of overlap is reduced as the thin filaments reach the H zone, which is composed of myosin tails. Because it is myosin heads that form cross-bridges, actin will not bind to myosin in this zone, reducing the tension produced by this myofiber.

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