PHYSIOLOGY
MUSCLE CONTRACTION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Which enzyme is responsible for degrading the neurotransmitter, ACh?
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Acetylcholinesterase
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ATPase
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Either A or B
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None of the above
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Explanation:
Detailed explanation-1: -Acetylcholinesterase (AChE) is a cholinergic enzyme primarily found at postsynaptic neuromuscular junctions, especially in muscles and nerves. It immediately breaks down or hydrolyzes acetylcholine (ACh), a naturally occurring neurotransmitter, into acetic acid and choline.
Detailed explanation-2: -Acetylcholinesterase degrades acetylcholine into choline and acetate molecules. Choline is then transported back into the presynaptic terminal and used in the synthesis of new acetylcholine. Figure 13.1. Acetylcholine is degraded into choline and acetate within the synaptic cleft via acetylcholinesterase.
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