MUSCLE PHYSIOLOGY

PHYSIOLOGY

MUSCLE ENERGETICS ATP AND CP

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The most likely cause of fatigue for a 1500 m runner is
A
dehydration.
B
glycogen depletion.
C
metabolic by-product accumulation
D
elevated body temperature.
Explanation: 

Detailed explanation-1: -Intracellular acidosis due mainly to lactic acid accumulation has been regarded as the most important cause of skeletal muscle fatigue.

Detailed explanation-2: -ATP metabolism biomarkers Under normal circumstances, the total adenine nucleotide pool (ATP+ADP+AMP) remains constant. When the ATP supply fails to meet the consumption of ATP during exercise, fatigue occurs.

Detailed explanation-3: -Intense exercise leads to muscle fatigue, a contractile and metabolic failure of contracting muscle to sustain desired work. It is widely accepted that the close relationship between intense exercise and the accumulation of metabolic by-products is the major cause of skeletal muscle fatigue.

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