MUSCLE PHYSIOLOGY

Detailed explanation-1: -In eukaryotes, the Krebs cycle reactions take place in the mitochondrial matrix, a dense solution that surrounds the mitochondria crests: in addition to water, the matrix contains all the enzymes necessary for the biochemical reactions of the cycle, coenzymes, and phosphates.

Detailed explanation-2: -Within the mitochondrion, the citric acid cycle occurs in the mitochondrial matrix, and oxidative metabolism occurs at the internal folded mitochondrial membranes (cristae).

Detailed explanation-3: -The Krebs cycle or TCA cycle (tricarboxylic acid cycle) or Citric acid cycle is a series of enzyme catalysed reactions occurring in the mitochondrial matrix, where acetyl-CoA is oxidised to form carbon dioxide and coenzymes are reduced, which generate ATP in the electron transport chain.

Detailed explanation-4: -Recall that glycolysis, stage I of cellular respiration, produces two molecules of pyruvate. These molecules enter the matrix of a mitochondrion, where they start the Krebs cycle.