MUSCLE PHYSIOLOGY

Detailed explanation-1: -In the citric acid cycle, the two carbons that were originally the acetyl group of acetyl CoA are released as carbon dioxide, one of the major products of cellular respiration, through a series of enzymatic reactions.

Detailed explanation-2: -The citric acid cycle: In the citric acid cycle, the acetyl group from acetyl CoA is attached to a four-carbon oxaloacetate molecule to form a six-carbon citrate molecule. Through a series of steps, citrate is oxidized, releasing two carbon dioxide molecules for each acetyl group fed into the cycle.

Detailed explanation-3: -In step two, an enzyme called aconitase converts citrate into isocitrate. Next, an isocitrate dehydrogenase enzyme oxidizes isocitrate, a six-carbon molecule, to a five-carbon -ketoglutarate. The carbon that was lost is released as carbon dioxide and one NADH is also formed.