MUSCLE PHYSIOLOGY

Detailed explanation-1: -Aerobic respiration is a process that utilizes the electron transport chain in order to oxidize glucose into energy. If a chemical were added that inhibited the electron transport chain, the cell would no longer be able to fully oxidize glucose. Therefore, oxygen consumption will decrease.

Detailed explanation-2: -Rotenone, carbon monoxide, cyanide, and oligomycin are poisons that target the electron transport chain and oxidative phosphorylation.

Detailed explanation-3: -Cytochrome oxidase inhibition has been shown to induce a hibernation-like or suspended-animation state. Reversible inhibition of cytochrome oxidase with carbon monoxide arrests embryogenesis in Caenorhabditis elegans embryos yet preserves their viability in hypoxic conditions.

Detailed explanation-4: -What effect would cyanide have on ATP synthesis? After cyanide poisoning, the electron transport chain can no longer pump electrons into the intermembrane space. The pH of the intermembrane space would increase, the pH gradient would decrease, and ATP synthesis would stop.