PHYSIOLOGY
MUSCLE ENERGETICS GLYCOLYSIS
|
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
|
|
Hexokinase
|
|
|
Phospho fructose isomerase
|
|
|
Aldolase
|
|
|
Dehydrogenase
|
Detailed explanation-1: -Glucose-6-phosphate (G6P) is changed into fructose-6-phosphate (F6P) by phosphoglucoisomerase (phosphoglucose isomerase) in the second step. This reaction also requires Mg2+. F6P can enter the glycolytic pathway from the next point. This reaction has a low free energy charge.
Detailed explanation-2: -Since glucose 6-phosphate and fructose 6-phosphate exist predominantly in their cyclic forms, PGI is believed to catalyse first the opening of the hexose ring to yield the straight chain form of the substrates.
Detailed explanation-3: -Answer and Explanation: The conversion of glucose-6-phosphate to fructose-6-phosphate is a necessary step to easily split a six-carbon sugar into three-carbon molecules.
Detailed explanation-4: -Phosphofructokinase catalyzes the conversion of fructose-6-phosphate to fructose-1, 6-diphosphate and is a key regulatory enzyme of glycolysis. The PFK molecule is a tetramer. Three isozyme subunits exist: muscle (M), liver (L), and platelet (P).