MUSCLE PHYSIOLOGY

Detailed explanation-1: -During glycolysis, glucose ultimately breaks down into pyruvate and energy; a total of 2 ATP is derived in the process (Glucose + 2 NAD+ + 2 ADP + 2 Pi–> 2 Pyruvate + 2 NADH + 2 H+ + 2 ATP + 2 H2O).

Detailed explanation-2: -1: Glycolysis produces 2 ATP, 2 NADH, and 2 pyruvate molecules: Glycolysis, or the aerobic catabolic breakdown of glucose, produces energy in the form of ATP, NADH, and pyruvate, which itself enters the citric acid cycle to produce more energy.

Detailed explanation-3: -In the first step, glucose ⇢ glucose-6-phosphate, ATP is used and gets converted into ADP. Similarly, in the third step, fructose-6-phosphate ⇢ fructose-1, 6-biphosphate, ATP is used. Thus, two ATPs are used in the first three steps of glycolysis. Hence, to split the glucose 2 molecules of ATPs are used.

Detailed explanation-4: -First ATP is produced when glyceraldehyde-3-phosphate ⇢ 1, 3 diphosphoglycerate. Secondly ATP is produced when phosphoenolpyruvate ⇢ pyruvate. These reactions occur twice for both molecules of 3-phosphate. Thus, a total of 4 ATPs are produced during glycolysis.

Detailed explanation-5: -These two steps take place two times in glycolysis. Hence, four molecules of ATP are synthesized. The steps such as conversion of glucose to glucose-6 phosphate and fructose-6 phosphate to fructose-1, 6 bisphosphate consumed two molecules of ATP. Thus net gain of ATP molecules in glycolysis is 2.