MUSCLE PHYSIOLOGY

Detailed explanation-1: -Explanation: The conversion of glucose to two pyruvate molecules in glycolysis produces a net total of two direct ATP. When fructose-1, 6-bisphosphate enters glycolysis, it bypasses the two steps involved that normally cost one ATP each, therefore, there is no required input and the net total is four produced ATP.

Detailed explanation-2: -Fructose-1, 6-bis phosphate can not directly enter into glycolysis. It should convert into glucose which yields 2 ATP molecules. Then this glucose enters into glycolysis and citric acid cycle which yields 38 ATP molecules.

Detailed explanation-3: -One molecule of ATP is utilised when glucose is converted to glucose-6-phosphate and the other is utilised when fructose-6-phosphate is converted to fructose-1, 6-bisphosphate. So, the net gain of ATP molecules during glycolysis is 2.