MUSCLE PHYSIOLOGY

Detailed explanation-1: -During glycolysis, glucose ultimately breaks down into pyruvate and energy; a total of 2 ATP is derived in the process (Glucose + 2 NAD+ + 2 ADP + 2 Pi–> 2 Pyruvate + 2 NADH + 2 H+ + 2 ATP + 2 H2O). The hydroxyl groups allow for phosphorylation. The specific form of glucose used in glycolysis is glucose 6-phosphate.

Detailed explanation-2: -Each reaction in glycolysis is catalyzed by its own enzyme. The most important enzyme for regulation of glycolysis is phosphofructokinase, which catalyzes formation of the unstable, two-phosphate sugar molecule, fructose-1, 6-bisphosphate 4start superscript, 4, end superscript.

Detailed explanation-3: -The energy to split glucose is provided by two molecules of ATP. As glycolysis proceeds, energy is released, and the energy is used to make four molecules of ATP. As a result, there is a net gain of two ATP molecules during glycolysis.

Detailed explanation-4: -Glycolysis produces only two net molecules of ATP per 1 molecule of glucose. However, in cells lacking mitochondria and/or adequate oxygen supply, glycolysis is the sole process by which such cells can produce ATP from glucose.