PHYSIOLOGY
MUSCLE ENERGETICS GLYCOLYSIS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Fructose-1, 6-bisphosphate
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Glucose
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Glucose-6-phosphate
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Glucose
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Detailed explanation-1: -Glucose is phosphorylated by hexokinase to form glucose-6-phosphate (G6P). The negative charge effectively traps G6P in the cell as it cannot pass through the membrane. This reaction consumes a molecule of ATP, so is spontaneous and irreversible.
Detailed explanation-2: -During glycolysis, glucose ultimately breaks down into pyruvate and energy; a total of 2 ATP is derived in the process (Glucose + 2 NAD+ + 2 ADP + 2 Pi–> 2 Pyruvate + 2 NADH + 2 H+ + 2 ATP + 2 H2O). The hydroxyl groups allow for phosphorylation. The specific form of glucose used in glycolysis is glucose 6-phosphate.
Detailed explanation-3: -Next, an isomerase reaction converts glucose-6-phosphate into fructose-6-phosphate by rearranging covalent bonds.