PHYSIOLOGY
MUSCLE ENERGETICS GLYCOLYSIS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Glyceraldehyde 3 phospate
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3 phosphoglycerate
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fructose 6 phosphate
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glucose 1, 6 bisphosphate
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Detailed explanation-1: -The second step of glycolysis involves the conversion of glucose-6-phosphate to fructose-6-phosphate (F6P). This reaction occurs with the help of the enzyme phosphoglucose isomerase (PI). As the name of the enzyme suggests, this reaction involves an isomerization reaction. Glucose and fructose are isomers.
Detailed explanation-2: -Glucose-6-phosphate (G6P) is changed into fructose-6-phosphate (F6P) by phosphoglucoisomerase (phosphoglucose isomerase) in the second step. This reaction also requires Mg2+. F6P can enter the glycolytic pathway from the next point. This reaction has a low free energy charge.
Detailed explanation-3: -The second reaction of glycolysis is the rearrangement of glucose 6-phosphate (G6P) into fructose 6-phosphate (F6P) by glucose phosphate isomerase (Phosphoglucose Isomerase).
Detailed explanation-4: -Fructose 6-phosphate lies within the glycolysis metabolic pathway and is produced by isomerisation of glucose 6-phosphate.
Detailed explanation-5: -Step 1: Glucose is phosphorylated by the enzyme hexokinase to form glucose 6-phosphate. Glucose gains energy by being phosphorylated at the expense of one ATP. Step 2: Glucose 6-phosphate is converted into its isomer, fructose 6-phosphate, by an isomerase enzyme.