MUSCLE PHYSIOLOGY

Detailed explanation-1: -Additionally, insulin promotes the uptake of circulating glucose into its target tissues, such as skeletal muscle and fat tissue, and thereby reduces the blood glucose level.

Detailed explanation-2: -Insulin facilitates entry of glucose into muscle, adipose and several other tissues. The only mechanism by which cells can take up glucose is by facilitated diffusion through a family of hexose transporters.

Detailed explanation-3: -In the liver, insulin helps promote the transport of glucose from the blood into hepatocytes, where it is further converted to glycogen, fatty acids, and triglycerides. In the skeletal muscles, insulin facilitates the uptake of glucose and amino acids from the bloodstream.

Detailed explanation-4: -Insulin and free C peptide are packaged in the Golgi into secretory granules which accumulate in the cytoplasm. When the beta cell is appropriately stimulated, insulin is secreted from the cell by exocytosis and diffuses into islet capillary blood.