PHYSIOLOGY
MUSCLE ENERGETICS GLYCOLYSIS
Question
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Phospho enol pyuruvic acid forms pyruvic acid by
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Enolase
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Pyuruvate kinase
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Dehydrogenase
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Kinase
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Explanation:
Detailed explanation-1: -In the canonical glycolysis pathway, the last step is catalyzed by PYK, which irreversibly converts PEP and ADP to pyruvate and ATP. PPDK is found in plants and a variety of microorganisms, catalyzing the reversible conversion of PEP, AMP and PPi to pyruvate, ATP and Pi.
Detailed explanation-2: -PEP is formed from the decarboxylation of oxaloacetate and hydrolysis of one guanosine triphosphate molecule. This reaction is catalyzed by the enzyme phosphoenolpyruvate carboxykinase (PEPCK). This reaction is a rate-limiting step in gluconeogenesis: GTP + oxaloacetate → GDP + phosphoenolpyruvate + CO.
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