MUSCLE PHYSIOLOGY

Detailed explanation-1: -Pyruvate, the product from glycolysis, is transformed into acetyl CoA in the mitochondria for the next step. The citric acid cycle, where acetyl CoA is modified in the mitochondria to produce energy precursors in preparation for the next step.

Detailed explanation-2: -After pyruvate is produced from glycolysis, it enters the mitochondria to begin aerobic respiration. Aerobic respiration begins with the conversion of pyruvate to acetyl CoA. This conversion takes place in three steps: decarboxylation, the reduction of NAD+, and the attachment of coenzyme A.

Detailed explanation-3: -Pyruvate is the end product of glycolysis. After glycolysis, the three-carbon molecule pyruvate is converted into the two-carbon molecule acetyl-coenzyme A (acetyl-CoA). This is carried out by a combination of three enzymes collectively known as the pyruvate dehydrogenase complex.

Detailed explanation-4: -How pyruvate from glycolysis is converted to acetyl CoA so it can enter the citric acid cycle.

Detailed explanation-5: -The three-carbon pyruvate molecule produced during glycolysis is converted to a two-carbon molecule of Acetyl CoA within the mitochondria.