MUSCLE PHYSIOLOGY

Detailed explanation-1: -Firstly, the link reaction produces one molecule of carbon dioxide and one molecule of reduced NAD. Its final product, acetyl coenzyme A, becomes a primary reactant of the Krebs cycle. The Krebs cycle produces one molecule of FADH2 and three molecules of NADH. It also produces two molecules of carbon dioxide.

Detailed explanation-2: -VCAC: Cellular Processes: The Citric Acid Cycle-An Overview: A Closer Look. The Citric Acid Cycle is a series of eight chemical reactions utilized by all aerobic organisms to generate energy. The pathway uses acetyl CoA and oxaloacetate to produce carbon dioxide, ATP, NADH, and FADH2.

Detailed explanation-3: -NADH (Nicotinamide Adenine Dinucleotide) is a molecule that carries electrons and hydrogen ions. It is produced during glycolysis and the citric acid cycle and is used as an electron donor in the Link Reaction.

Detailed explanation-4: -The link reaction occurs in the mitochondrial matrix. It dehydrogenates and decarboxylates the three-carbon pyruvate to produce the two-carbon acetyl CoA that can enter the Krebs Cycle.

Detailed explanation-5: -Pyruvate loses a carbon atom to become a 2-carbon compound. This carbon atom is released in the form of carbon dioxide. The 2-carbon compound is oxidized, and it transfers electrons to N A D . The coenzyme N A D becomes reduced NAD (NADH) as it gains a hydrogen and two electrons.