MUSCLE PHYSIOLOGY

Detailed explanation-1: -In this phase, the starting molecule of glucose gets rearranged, and two phosphate groups are attached to it. The phosphate groups make the modified sugar-now called fructose-1, 6-bisphosphate-unstable, allowing it to split in half and form two phosphate-bearing three-carbon sugars.

Detailed explanation-2: -The phosphorylation of glucose maintains the downhill gradient for glucose metabolism and extramitochondrial glucose flux through the pentose phosphate pathway. Induction of the pentose phosphate pathway and the generation of NADPH may also contribute to protection against cell death.