PHYSIOLOGY
MUSCLE ENERGETICS GLYCOLYSIS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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What is the major energy generating step in glycolysis?
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Phosphofructokinase
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Hexokinase
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Phosphoglycerate kinase
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Glyceraldehyde-3-P dehydrogenase
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Explanation:
Detailed explanation-1: -Glyceraldehyde 3-phosphate dehydrogenase (abbreviated GAPDH) (EC 1.2. 1.12) is an enzyme of about 37kDa that catalyzes the sixth step of glycolysis and thus serves to break down glucose for energy and carbon molecules.
Detailed explanation-2: -The glycolytic substrate G3P is oxidized by the coenzyme NAD+, then separates from the enzyme by phosphorolysis in the presence of Mg2+, with incorporation of a phosphate (Pi) forming 1, 3-diphosphoglycerate (1, 3-diPG). This energy-rich bond is finally used to produce the glycolytic ATP.
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